Purpura fulminans Images
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Purpura fulminans: Purpura fulminans beginning in the abdominal region in the context of E. coli sepsis in a 55-year-old man (lethal outcome).

Purpura fulminans: blistered lifting of the skin in the area of the left flank.

Purpura fulminans - reflected light microscopy (focus in the abdominal area, section): As a result of intracapillary thrombus formation, the central capillaries appear livid, dot-shaped or line shaped in the reflected light plane. Livid background pigmentation due to erythrocyte exocytosis.

Purpura fulminans - reflected-light microscopy: advanced thrombosis and stagnation hypoxia The entire papillary body is filled with agglutinated erythrocytes, recognizable by the small, livid, round or polygonal, cobblestone-like areas (negative pigment network).