Promethazine

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Antihistamine, anti-allergic, sedative.

Half-life
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8–15 h

Indication
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Dosage and method of use
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  • Adults/youth/children > 10 years 1-3 times/day 25-50 mg p.o.
  • Children 5-10 years: 1-3 times/day 25 mg p.o.
  • Children 2-5 years: 1-2 times/day 25 mg p.o.
  • Children 1-2 years: 1-3 times/day 25 mg p.o.

Undesirable effects
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In case of systemic application: cataract (long-term use), venous thrombosis, weight gain, bronchial asthma, Quincke's edema (see angioedema), agitation, coma, transient myopia, reduced tear production.

Interactions
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Amikacin increases the neuromuscular blockade.

Contraindication
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Hypersensitivity to phenothiazines, coma, shock, intra-arterial and subcutaneous injection.

Preparations
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Atosil, proneurine 25

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Last updated on: 29.10.2020