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Nevus lipomatosus cutaneus superficialisD23.L

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Adipose tissue nevus of the skin; Hoffmann-Zurhelle's nevus lipomatosus cutaneus superficialis; Lipoma of the skin; lipoprotein nevus of the skin; Naevus lipomatodes cutaneus superficialis; Nevus lipomatodes cutaneus superficialis (Hoffmann-Zurhelle); NLCS; Skin lipoma; Superficial cutaneous nevus lipomatosus of Hoffmann-Zurhelle

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HistoryThis section has been translated automatically.

Hoffmann and Zurhelle, 1921

DefinitionThis section has been translated automatically.

Circumscribed adipose tissue nevus (lipoma of the skin) with development of fatty tissue lobules in the dermis, which develops from ectopic adipocytes of the dermis. In rare cases, these "nevoid skin lipomas" are combined with lipomas of deeper organ systems, e.g. muscles.

ManifestationThis section has been translated automatically.

Since birth; m>w;

LocalizationThis section has been translated automatically.

loins and glutaeal region.

Clinical featuresThis section has been translated automatically.

Soft, skin-coloured to yellow or yellow-red, isolated or more frequently aggregated papules or plaques, existing since birth, grouped over an area of 1-10 cm, as well as flat, soft, smooth or even wart-like nodules, sometimes with a cauliflower-like aspect.

Rarely described are giant cutaneous fat tissue nevi that extend over a large area (e.g. back).

Complex hamartomas in combination with trichofolliculomas, nevus sebaceus are known.

HistologyThis section has been translated automatically.

The epidermis is normal or slightly acanthotic. Already at the overview enlargement, fat cell heterotopias - small or even larger lobules of normal adipose tissue - are conspicuous in the upper dermis. These islands of adipose tissue in the dermis show no connection with subcutaneous fat or skin appendages. Estimates of fat in the dermis vary from 10-50%.

Differential diagnosisThis section has been translated automatically.

To what extent the "Naevus lipomatosus cutaneus superficialis" is identical with the"congenital fibrolipomatous hematoma of the calcaneus" described by Larralde de Luna et al. 1990 is to be discussed.

TherapyThis section has been translated automatically.

For cosmetic reasons, excision if necessary.

LiteratureThis section has been translated automatically.

  1. Haas N, Wegner T (2004) Naevus lipomatodes cutaneus superficialis (Hoffmann-Zurhelle). dermatologist 55: 376-378
  2. Hoffmann E, Zurhelle E (1921) On a nevus lipomatodes cutaneus superficialis of the left glutaeal region. Arch Dermatol Syphil (Berlin) 130: 327-333
  3. Jung ST et al (2012) Giant nevus lipomatosus cutaneous superficialis
    withintramuscular lipomatosis. J Am Acad Dermatol 67:e168-70
  4. Stenger D et al (1986) Naevus lipomatodes cutaneus superficialis (Hoffmann-Zurhelle). Z Hautkr 61: 50

  5. Sendhil Kumaran M et al (2013) Nevus lipomatosus superficialis unseen or unrecognized: a report of eight cases. J Cutan Med Surgery 17:335-339

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer