Neurom kutanes (overview) - Altmeyers Encyclopedia

Definition
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Benign, tumorous growth of the coreless axons and their core-rich medullary sheaths derived from mixed peripheral nerves. Depending on the clinic, histology and etiology, different variants are seen. Only in the case of the ganglioneuroma, which is very rare in the skin, ganglion cells are additionally found in the tumor parenchyma.

Classification
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Classification of true cutaneous neuromas:

Ganglioneurom
Fibrillary Neuromas:
- Traumatic neuroma (scar neuroma, amputation neuroma, special form: Morton neuroma)
- Idiopathic solitary or multiple neuromas (see also neurofibroma, plexiformes (encapsulated))
- Multiple skin and mucous membrane neuroma in multiple neuroma syndrome ( MMN syndrome)
- Neurom, encapsulated
- (Rudimentary polydactyly).

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Dermatology

Neurofibroma

Most frequent neurogenic tumour, which occurs solitary or as part of neurofibromatosis .

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Clinical features
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Skin-coloured, solitary or multiple, easily movable, occasionally painful, lenticular to pea-sized, subcutaneous nodule with soft to derbelastic consistency.

Differential diagnosis
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Schwannoma; neurofibroma.

Literature
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Altmeyer P (1991) Multiple systematized neuromas of the skin and mucosa. Dermatologist 32: 240-244
Kutzner H et al. (1990) The solitary encapsulated neuromas. dermatologist 41: 620-624
Leverkus M et al (2003) Multiple unilateral schwannomas: segmental neurofibromatosis type 2 or schwannomatosis? Br J Dermatol 148: 804-809
Mobbs RJ et al (2003) Treatment of painful peripheral neuroma by vein implantation. J Clin Neurosci 10: 338-389
Stahl S et al (2002) Surgical treatment of painful neuroma in medial antebrachial cutaneous nerve. Ann Plast Surgery 48: 154-158