Synonym(s)
encapsulated neurofibroma; palisaded encapsulated neuroma (Reed); solitary encapsulated neuroma
HistoryThis section has been translated automatically.
Reed, 1972
DefinitionThis section has been translated automatically.
Benign neurogenic tumor with nodular proliferation of nerve fibers and typical at least partial encapsulation, which is often misunderstood clinically and histologically.
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ManifestationThis section has been translated automatically.
Mostly occurring in older people.
LocalizationThis section has been translated automatically.
Especially face with emphasis on regions close to the mucous membranes.
Clinical featuresThis section has been translated automatically.
Solitaire, skin-coloured, plump, shiny, hemispherical nodule.
HistologyThis section has been translated automatically.
Spindle cell tumour located in the upper corium and surrounded by a narrow capsule of Schwann cells. Partial palisade position of the nuclei, numerous shrinkage fissures. Often small marginal nodules.
Direct ImmunofluorescenceThis section has been translated automatically.
S-100 and vimentin-positive cells, capsule only vimentin-positive.
Differential diagnosisThis section has been translated automatically.
- Clinical presentation: Basal cell carcinoma, melanocytic nevus.
- Histological: Schwannoma, leiomyoma.
TherapyThis section has been translated automatically.
In case of pain, functional or cosmetic disorder: excision.
LiteratureThis section has been translated automatically.
- Dubovy SR et al (2001) Palisaded encapsulated neuroma (solitary circumscribed neuroma of skin) of the eyelid: report of two cases and review of the literature. Br J Ophthalmol 85: 949-951
- From L et al (1987) Neoplasms and Hyperplasias of Neural and Muscular Origin. In: Fitzpatrick TB et al. Dermatology in general medicine. 3rd ed. 1053-1059
- Jordan RC et al (2003) Oral spindle cell neoplasms: a review of 307 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95: 717-724
- Kutzner H et al. (1990) The solitary encapsulated neuromas. dermatologist 41: 620-624
- Reed RJ et al (1972) Palisaded, encapsulated neuromas of the skin. Arch Dermatol 106: 865-870
Recommended articles
Incoming links (1)
Palisaded encapsulated neuroma;Outgoing links (6)
Basal cell carcinoma (overview); Dermis; Excision; Leiomyoma (overview); Nevus melanocytic (overview); Schwannom;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer