Natamycin

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Polyene antifungal from Streptomyces natalensis.

Natamycin is authorised as a food additive under the number E 235 in the EU as a preservative.

Indication
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Fungal infections of the mouth and throat area, the eyes, eyelids or tear ducts (especially in the case of infections caused by yeast fungi).

Pregnancy/nursing period
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Strict indication during pregnancy.

Dosage and method of use
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Sucking pastilles: 4-6 times/day 1 tbl. to melt in the mouth. Eye ointment: Apply 1 cm of ointment into the conjunctival sac every 2 hours.

Standard concentration
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Eye ointment: 1%.

Undesirable effects
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Allergic skin reactions, diarrhea.

Interactions
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External clotrimazole or oxiconazole leads to a mutual reduction in effectiveness.

Contraindication
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Hypersensitivity to the active substance.

Preparations
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Pimafucine, Pima-Biciron N Eye ointment

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Last updated on: 29.10.2020