Microsphere B35.0

Highly contagious, non-abscessing folliculitis caused by microsporum species.

Among the proven cases of dermatomycoses, the proportion of infections caused by microsporum species is about 4% (Heidrich D et al. 2015)

The capillitium (tinea capitis) is preferably infested by children or young people.

Infestation of the entire integument(Tinea corporis) possible (but rare)

In tinea capitis about 50% of cases are caused by microsporum species .

M. canis (zoophilic, carriers are mainly cats; Nardoni S et al. 2015), M . audouinii (anthropophilic); M . gypseum (geophilic)

The zoophilic M. canis often spreads endemically in kindergartens and schools. Direct physical contact or transmission through infected objects.

Almost exclusively children and adolescents are affected (close contact with infected "cuddly toys").

Capillitium: Initially multiple, small, pityriasiform scaling, slow-growing, confluent to polycyclically limited areas with hairs broken off just above the scalp (comparison with a badly mowed meadow).

Face, neck, trunk and extremities: Anular, light red to deep red, bordered, Collerette-like scaly plaques. In most cases there is clear itching.

Diagnosis: Pathogen detection in the native preparation and in culture, green fluorescence in wood light.

Broad-spectrum antifungals such as bifonazole (e.g. Mycospor cream) or ciclopirox (e.g. Ciclopoli®).

Source of infection: Find infected animal (cat, dog) and have it treated by veterinarian.

• Fluconazole (1mg/kgkgKG p.o.): To prevent recurrences, the treatment period should extend beyond the healing period and may take several months if severe.
• Alternative: Itraconazole (e.g. Sempera Kps.) 100 mg/day show good results in individual case reports, but the active substance is not yet approved for children due to lack of experience.
• Alternative: Ketoconazole
• Alternative: Griseofulvin (e.g. Likuden), adults 500-1000 mg/day, children 6-7 mg/kg bw/day.

An herbal mixture of different oils: Litsea cubeba (1%), Illicium verum (0.5%), Foeniculum vulgare (0.5%), and Pelargonium graveolens (0.5%) showed antifungal activity against M. canis arthrospores (Nardoni S et al. 2015).

The term "microsporum" has become established colloquially as a designation for a specific pathogen (analogous to "trichophytosis"). However, the respective clinical picture caused by microsporum species, e.g. in the case of infestation of the capillitium, is referred to as tinea, e.g. tinea capitis.

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