Synonym(s)
3-D histology; micrographically controlled surgery; MKC; Surgery microscopically controlled
DefinitionThis section has been translated automatically.
Modification of the Mohs technique, which has become the standard method in European countries for the treatment of therapeutically complicated tumours.
IndicationThis section has been translated automatically.
The MKC is to be requested from:
- Sclerodermiform basal cell carcinoma of the facial region
- Basal cell carcinoma in the medial and lateral corner of the eye
- Basal cell carcinoma of the eyelid
- Basal cell carcinoma of the nose and ear
- Basal cell carcinoma recurrence
- carcinoma verrucosum
- Melanoma, malignant
- Lentigo maligna.
ImplementationThis section has been translated automatically.
- Excision of the tumor with already intraoperatively applied suture marker for topographical orientation. Fixation of the preparation with formalin and preparation of marginal incisions on all sides and depth according to the suture marking.
- Examination is usually performed on a paraffin incision (or, if possible, on a cryostat incision).
- With this method, it is possible to obtain a complete histogram of the entire excidate outer surface (3-D histology) and thus an exact assessment of the tumor's expansion.
- The advantages of this method are low recurrence rates and the greatest possible protection of the tissue.
- If the edge incisions are free of tumours, the situational defect coverage is carried out.
LiteratureThis section has been translated automatically.
- Breuninger H et al. (1994) The complete histological representation of the cut edges of a skin tumour excise (3D histology) in one sectional plane using the flounder technique. Nude Dermatol 20: 7-10
- Fleischman M et al (2003) Informed consent in dermatologic surgery. Dermatol Surgery 29: 952-955
Prof. Dr. med. Peter Altmeyer