Meyerson-naevus L30.8

Author: Prof. Dr. med. Peter Altmeyer

Last updated on: 08.03.2023

Synonym(s)

Halo dermatitis around nevus cellnaevi; Halo-eczema around Naevuszellnaevi; Meyersonnaevus; Meyerson Naevus; Meyerson Phenomenon; Nevuscellnaevus

History
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Meyerson 1971

Definition
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Spontaneously occurring, halo-shaped eczematous reaction around a melanocytic nevus, corresponding to the pigment-free halo nevus.

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Dermatology

Spongiosis

Dissociation of the epidermis and the epithelial adnexal structures due to an intercellular edema with cons...

Etiopathogenesis
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Unexplained, a Köbner phenomenon is discussed in the context of atopic eczema, pityriasis rosea or psoriasis vulgaris.

Manifestation
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Predominantly occurring in middle-aged men.

Clinical features
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Sudden, halo-shaped redness and scaling of most or all of a patient's melanocytic nevi in the form of a reddened, slightly scaly, 0.1- 1.0-cm-wide fringe. Occurrence usually in summer. Such (isomorphic irritant) effects are also observed in seborrheic keratoses, e.g. in psoriasis vulgaris (Meyerson phenomenon).

Histology
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Enforcing the melanocyte nests with an infiltrate containing numerous eosinophil granulocytes. In the marginal area epidermal changes in the form of parakeratosis, spongiosis, acanthosis as well as epidermotropy of leucocytes.

Differential diagnosis
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Halo-nevus.

Therapy
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Mild antiecematous local therapy, e.g. with 1% hydrocortisone in Vaseline. Later excision.

Progression/forecast
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Spontaneous regression tendency of eczema. The melanocytic nevi always remain unchanged.

Note(s)
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Over time, cases of "eczematous" or even psoriatic reactions have been described around basal cell carcinomas, spinocellular carcinomas, dermatofibromas, seborrheic keratoses and nevi flammei, so that the generalizing name "Meyerson phenomenon" has become established.

Literature
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Wall A, Disciple H (1991) Halo dermatitis around naevuscellnaevi (Meyer- son-Naevi). Act Dermatol 17: 22-24
Nicholl's DSH, Mason GH (1988) Halodermatitis around a melanocytic naevus: Meyerson's naevus. Br J Dermatol 118: 125-129
Hofer T (2002): Meyerson-Naevus as primary medallion of a pityriasis rosea. Gibert. dermatologist 53: 338-341
Meyerson LB (1971) Peculiar papulous squamous eruption involving pigmentet naevi. Arch Dermatol 103: 510-512
Simopn V et al (2011) Eczema disguises a naevus flammeus - the Meyerson phenomenon. JDDG 9: 305-307