Hydrocortisone

Author: Prof. Dr. med. Peter Altmeyer

Co-Autor: Hadrian Tran

All authors of this article

Last updated on: 10.04.2021

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Synonym(s)

Hydrocortisone

Definition
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Weak non-halogenated glucocorticoid.

Half-life
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1,5 h

Indication
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Status asthmaticus, allergic reactions, eczema; inflammatory, allergic and pruriginous dermatoses.

In addition, substitution therapy for adrenocortical insufficiency, acute adrenocortical insufficiency (e.g. Addisonian crisis) and adrenogenital syndrome (inhibition therapy to reduce ACTH release).

Systemic or topical administration for autoimmune diseases.

Dosage and method of use
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  • Ointment/cream: Apply a thin layer 1-3 times/day on the affected skin areas.

    Remember!

    Duration of application max. 8 weeks.
  • Systemic: 100-250 mg i.v.

Standard concentration
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0.25-3% in ointments, creams and lotions.

Preparations
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Ficortril, Dermoposterisan, Hydrogalene, Hydro-Wolff, Hydrocortisone Hoechst

Note(s)
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Standard value: The reference range is between 171 and 536 nmol/l in the morning, between 64 and 337 nmol/l in the afternoon and < 138 nmol/l at night

Pathologically increased: Cushing's syndrome, obesity, anorexia nervosa, chronic alcoholism, severe acute and chronic general diseases, endogenous depression, hyperestrogenism, iatrogenic and paraneoplastic

Pathologically debased: Addison's syndrome

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Last updated on: 10.04.2021