Melanoerythroderma L81.4

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 24.08.2021

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Synonym(s)

Erythrodermia with Marked Pigmentation

Definition
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Fuzzily defined (outdated), purely descriptive term for a polyätiological variant or healing phase of erythroderma in which, in addition to the universal red colour of the erythroderma, an additional bronze-coloured pigmentation (histologically pigment insufficiency) of the entire integument is present.

Etiopathogenesis
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Often unknown. May appear as a paraneoplastic syndrome; also symptom of cutaneous T-cell lymphoma or rare, severe drug side effects.

Clinical features
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Generally clinically severe clinical picture with universal, diffuse brown (red) discoloration of the entire integument. Often fine or coarse lamellar scaling is seen. Poikilodermatous aspect also possible. There is usually severe pruritus and generalized (dermatopathic -reactive) lymphadenectomy.

Histology
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Non-specific.

Therapy
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Treatment of the underlying disease, otherwise bland greasy external agents such as water-containing wool wax alcohol ointment (or Eucerin cum aq.), ash base cream, linola fat or others.

Note(s)
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The term "melanoerythroderma" is not a diagnosis in the true sense of the word, but rather a description of a universal erythrodemic disease state.

Literature
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  1. Borrás-Blasco J et al (2001) Erythrodermia induced by omeprazole. Int J Clin Pharmacol Ther 39:219 w23.
  2. Iliescu V et al.(1997) Erythrodermia sézary with immunological deficiency and antibodies against human albumin. Acta Med Scand 197(1-2):141-144. Kiessling W et al.(1959) Melano-erythrodermia with cachexia. Arch Klin Exp Dermatol 208:579-591.
  3. Mori S et al (1988) Postoperative erythrodermia (POED), a type of graft-versus-host reaction (GVHR)? Pathol Res Pract 184:53-59.
  4. O'DONOVAN WJ (1950)Exfoliative erythrodermia with lymphadenopathy. Proc R Soc Med. 43:563-564.
  5. Oztas P et al (2006) Imatinib-induced erythrodermia in a patient with chronic myeloid leukemia. Acta Derm Venereol 86:174-175.
  6. Sequeira JH (1919) Case of Erythrodermia with Lymphatic Leukaemia. Proc R Soc Med.12(Dermatol Sect):54-56.
  7. Wigley JE (10947) Exfoliative erythrodermia with marked pigmentation. Proc R Soc Med 40:246-247.

Outgoing links (2)

Erythrodermia; Wool wax alcohols;

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 24.08.2021