Keratosis areolae mammae naeviformis Q82.5

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Breast Keratoses; Breast Keratosis; Hyperkeratosis and papillomatosis areolae mammae; Hyperkeratosis areolae mammae idiopathica; keratosis areolae; Keratosis of the nipple; Nevoid hyperkeratosis of the nipple; Nevoid hyperkeratosis of the nipple and areola; nevus papillomatosus verrucosus of the nipple

Definition
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Typically unilaterally occurring, nevoidal malformations of the nipple court.

Occurrence/Epidemiology
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Preferably with women.

Etiopathogenesis
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The definition presupposes an investment-related "naeviform" process. S.a. Keratosis areolae mammae acquisita.

Clinical features
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Dirty brownish to blackish, hyperkeratotic, wart-like growths of the nipple skin.

Therapy
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A causal therapy is not possible. Blande nourishing therapy with mild keratolytic externals. This can bring about a moderate improvement of the findings. However, the therapy is to be applied permanently. Good results were achieved with an ointment containing calcipotriol.

Progression/forecast
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Nothing is known about spontaneous regressions.

Note(s)
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Double-sided nipple keratoses should be classified as a paraneoplastic syndrome(Keratosis areolae mammae acquisita).

Literature
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  1. Fenniche S et al (2010) Images in clinical medicine. Nevoid hyperkeratosis of the nipple and areola. N Engl J Med 362:1618
  2. Guevara-Gutiérrez E et al (2008) Unilateral nevoid hyperkeratosis of the nipple and areola treated with topical calcitriol. Actas Dermosifiliogr 99::500-501

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Last updated on: 29.10.2020