Hydroxycin

Definition
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Antihistamine, tranquilizer and antiallergic.

Indication
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Itching with urticaria and neurodermatitis. Anxiety, tension and restlessness, psychogenic sleep disorders, premedication before surgery.

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Dermatology

Drug reaction fixe

Localized, patchy or plaque-like, also bullous or exfoliative drug reaction,which occurs in a temporal conn...

Dosage and method of use
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Itching: Children 6-10 yrs. 25-50 mg/day. Adults and children > 10 years 37.5-75 mg/day.
anxiety, tension and restlessness: adults and children > 10 years 37.5-75 mg/day in 2-3 weeks.
Psychogenic sleep disorders: adults and children > 10 years 37.5-75 mg/day in the evening before going to bed.
Premedication before surgery: children 6-10 years. 25 mg. Adults and children > 10 years. 50 mg the day before surgery.

For older and weakened patients the lowest maintenance dose. Take Tbl. before meals with alcohol-free liquid.

Undesirable effects
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Exanthema; urticaria; drug reaction, fixed (especially oral or genital; rarely on the buttocks, see also Baboon syndrome); rarely cerebral seizures. Sedation, signs of excitation in infants, glaucoma, visual disturbances, dry mouth, gastrointestinal disturbances, rarely micturition disturbances.

Interactions
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Phenytoin: reduced effectiveness. Anticholinergic drugs: Enhanced action. Central antihypertensive drugs: Enhanced sedation. Adrenalin: drop in blood pressure.