Finger ankle pads real M72.1

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Ankle calluses; Ankle pads real; Calluses; Finger calluses; Horn calluses; Idiopathic knuckle pads; Joint Calluses; Knuckle pads; Malleolus; Pachydermodactyly; Real ankle pads; Real knuckle pads; Toe calluses; Tylositates articuli

History
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Garrod, 1893

Definition
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Superficial fibromatosis is a circumscribed, cushion-like, fibrotic thickening that is located on the stretching side above the finger (toe) joints.

Etiopathogenesis
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Fibromatosis of unknown etiology. Often in combination with other fibromatoses of the adult(Dupuytren's contracture, induratio penis plastica); not infrequently a tendency to keloid is observed.

S.a. the occurrence of idiopathic Knuckle Pads in:

Some authors state an autosomal dominant inheritance.

Manifestation
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Mostly occurring in youth or early adulthood.

Localization
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Usually symmetrical over the dorsal sides of the middle joints of the 2nd to 5th finger, more rarely of the toes.

Clinical features
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Pea-size, flat raised, coarse, pad-like, skin-coloured or yellow-brown papules or plaques with a granular, bumpy, woolly surface.

Histology
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Differential diagnosis
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Therapy
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If necessary, intrafocal triamcinolone injection(e.g. Volon A diluted 1:1 with Scandicain).

Progression/forecast
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Training over the years, no regression.

Note(s)
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Fibromatoses are a heterogeneous group of new formations of connective tissue, which nosologically stand between reactive new formations and true neoplasias. Especially congenital forms and familial occurrence and the detection of mutations (see below fibromatosis, hyaline juvenile) speak, at least for some members of this group of diseases, for a genetic basis.

Literature
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  1. Chamberlain AJ et al (2003) Pachydermodactyly: a forme fruste of knuckle pads? Australas J Dermatol 44: 140-143
  2. Garrod AE (1893) On an unusual form of nodule upon joints of the fingers. St Bartholomew's Hosp Rep 29: 157-161
  3. Hayashi M et al (2012) Case of epidermolytic palmoplantar keratoderma with knuckle pads. J Dermatol 39:84-87

  4. Hyman CH et al (2013) Report of a family with idiopathic knuckle pads and review of idiopathic and disease-associated knuckle pads. Dermatol Online J 19:18177

  5. Lin Z, Zhao J et al (2015) Loss-of-function mutations in CAST Cause Peeling Skin, Leukonychia, Acral Punctate Keratoses, Cheilitis, and Knuckle Pads. On J Hum Genet 96:440-447

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Last updated on: 29.10.2020