Eye diseases, skin changes jeweilige Erkrankung

Clinical classification of skin and eye constellation:

• Monitor signs and disorders for combined diseases of the skin and eyes:
  • Arcus senilis corneae
  • Arteritis temporalis
  • Atopic eczema (keratitis)
  • Behçet 's disease (acute iridocyclitis with red eye and radiating pain: ciliary neuralgia)
  • Candidiasis, chronic mucocutaneous (CMC)
  • Conjunctivitis allergica (chemosis, itching, watering eyes, foreign body sensation)
  • Erythema exsudativum multiforme (conjunctivitis)
  • Gonoblenorrhea
  • Herpes simplex (keratitis dendritica -infection of the cornea)
  • Hidroa vacciniformia
  • HIV infection (acute iridocyclitis with red eye and radiating pain: ciliary neuralgia)
• Corneal opacities:
  • Angiokeratoma corporis diffusum: cornea verticillata.
  • Hereditary benign intraepithelial dyskeratosis: Fine, cloudy, gelatinous plaques overgrowing the cornea.
  • Ichthyosis vulgaris, autosomal dominant: Superficial corneal opacities.
  • Ichthyosis vulgaris, X-linked recessive: Deep-seated corneal opacities.
  • Pachyonychia congenita: Later with corneal dystrophy.
  • Hutchinson's sign II (zoster affection of the eye: 75% probability)
  • Hyperlipoproteinemia type II (arcus senilis)
  • Keratoconjunctivitis photoelectrica (after UV exposure)
  • Keratosis lichenoides chronica (kerato-conjunctivitis)
  • Staphylococcal scalded skin syndrome (kerato-conjunctivitis)
  • Lyme disease (eye involvement)
  • Melanoma, malignant of the conjunctiva
  • Onchocerciasis (skin and eye involvement)
  • Paraproteinemia:
    • Keratitis filiformis
    • Sicca symptoms
• Pemphigoid, scarring (catarral or purulent conjunctivitis, scarring, adhesions and shrinkage of eyelid and conjunctiva = symblepharon)
• Pemphigus vulgaris (conjunctivitis)
• Phospholipid antibody syndrome (central arteries of the eye)
• Polyarteritis nodosa, systemic (ocular symptoms: fundus hypertonicus)
• Polychondritis recidivans et atrophicans
• Caterpillar conjunctivitis
• Reiter's syndrome (acute iridocyclitis with bright red eye and radiating pain: ciliary neuralgia)
• Rosacea (involvement of the eyes: blepharitis, conjunctivitis)
• Sarcoidosis (Acute iridocyclitis with high red eye and radiating pain: ciliary neuralgia; Koeppe's nodule: nodules located at iris ruff).
• Sicca symptomatology: e.g. associated with:
  • Sjögren's syndrome
  • Collagenoses
  • Sarcoidosis
  • Conjunctivitis allergica
  • Pemphigoid, scarring
  • Sjögren's syndrome
  • Scleroderma, systemic (eyes: cataract, sicca symptoms)
• Stevens-Johnson syndrome (kerato-conjunctivitis)
• Still syndrome (ocular lesions: iridocyclitis; band keratopathy)
• Syphilis acquisita (Argyll-Robertson phenomenon: pupils are narrow and rounded; reflex pupillary rigidity; iris nodules)
• Toxic epidermal necrolysis
• Tuberculosis (kerato-conjunctivitis scrofulosa)
• Vasculitis in essential cryoglobulinemia
• Wegener's granulomatosis
• Wilson, M. (Kayser-Fleischer corneal ring)
• Xanthogranuloma, necrobiotic with paraproteinemia
• Xeroderma pigmentosum (affection of eyelids, conjunctiva)
• Zoster ophthalmicus
• cytomegaly.
• Rare syndromes with skin and eye involvement:
  • Ablepharon macrostomy syndrome
  • ADULT syndrome: Clinical picture: Split hand and split foot. Eye: Atresia of the tears
  • Albinism totalis (sunglasses)
  • Waardenburg syndrome (ocular malformations; heterochromia)
  • Albinism, oculocutaneous, tyrosinase-negative (transparent iris, ocular fundus completely free of pigment)
  • Albinoidism, oculocutaneous (pigmentation of the ocular fundus)
  • Angiokeratoma corporis diffusum (cornea verticillata)
  • Atrichia congenita diffusa
  • Bannayan-Riley-Ruvalcaba syndrome
  • Birt-Hogg-Dubé syndrome(renal cysts, hamartomas; eyes: retinopathies, chorioretinopathies, glaucoma)
  • Chondrodysplasia calcificans congenita (skin, skeletal and ocular abnormalities)
  • Cronkhite-Canada syndrome (eye malformations)
  • Crouzon syndrome (eye anomalies)
  • Cutis marmorata teleangiectatica congenita
  • Dubowitz syndrome
  • Dyskeratosis, hereditary, benign intraepithelial
  • Dyskeratosis congenita
  • Dysplasia, hidrotic ectodermal
  • Epidermolysis bullosa junctionalis with pyloric atresia
  • Erythrokeratodermia progressiva, Burns type (missing eyebrows and eyelashes)
  • Goldenhar syndrome
  • Gorlin-Chaudhry-Moss syndrome
  • Hermansky-Pudlak syndrome
  • Hypotrichosis congenita hereditaria generalisata (rarefied eyebrows)
  • Incontinentia pigmenti achromians
  • Keratosis palmoplantaris circumscripta seu areata
  • LEOPARD syndrome
  • Marfan syndrome (bilateral lens subluxations = lens flutter)
  • Möbius syndrome (infantile eye muscle atrophy)
  • Nevus fuscocoeruleus ophthalmomaxillaris
  • Nail-patella syndrome
  • Neurofibromatosis (eyes: Lisch nodules)
  • Pachyonychia congenita
  • Progeria-like syndrome (deep-set eyes, prognathism)
  • Schimmelpenning-Feuerstein-Mims syndrome
  • Sjögren-Larsson syndrome (in individual cases eye fundus anomalies)
  • Sphingolipidoses (characteristic ocular fundus changes)
  • Sturge-Weber-Krabbe syndrome (buphthalmos, hydrophthalmos)
  • Trichooculodermovertebral syndrome
  • Tuberous sclerosis
  • Ullrich-Turner syndrome (cataract)
  • Neurofibromatosis-Noonan syndrome (hypertelorism).