DefinitionThis section has been translated automatically.
Generic term for drugs that prevent the binding of the HI virus to the cell membrane of CD4-positive cells. S.u. Enfuvirtide.
EffectsThis section has been translated automatically.
When HIV enters the CD4 cell, there are three key sites to prevent contact: the binding of HIV to the CD4 receptor, the binding to coreceptors and finally the fusion of virus and cell. Entry inhibitors prevent the fusion of virus and target cell.
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IndicationThis section has been translated automatically.
Therapy of HIV infections; preparations are prescribed in combination with other antiretroviral drugs (see below HAART).
Undesirable effectsThis section has been translated automatically.
The most important adverse effects of the respective drugs are listed in table form under HIV infection.
LiteratureThis section has been translated automatically.
- Plettenberg A et al (2003) RADATA - an expert system for the optimization of antiviral therapy decisions. Documentation and analysis of disease progression. Fuzeon cohort. www.radata.de
Prof. Dr. med. Peter Altmeyer