Diosmin

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 18.04.2024

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Synonym(s)

3`,5,7-trihydroxy-4`-methoxyflavone; Barosmine; CAS No.: 520-27-4; Diosminum

Definition
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Flavone glycoside (its aglycone = diosmetin) which is used as a vein remedy and is found in shepherd's purse, among other things, as an active ingredient.

Pharmacodynamics (Effect)
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It is suspected that the catechol-O-methyltransferase (COMT) inhibits the breakdown of norepinephrine. The influence of norepinephrine on the contractile elements of the vein wall is thus increased and vein function is improved. Further toning of the venous wall, increase of venous reflux and increase of capillary resistance.

Indication
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Dosage and method of use
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2-3 times/day 1 Kps. p.o.

Preparations
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Tovene

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Last updated on: 18.04.2024