Cytomegalovirus ulcer B25.9

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Cytomegaly ulcus

Definition
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Torpidal, ulcerous, local cytomegalovirus infection (see below cytomegaly), which occurs in immunocompromised patients.

Etiopathogenesis
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CMV infection, the origin is unclear; both disseminated and local infections are discussed.

Localization
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Mainly on the genital region, perianal region, also orally (Drozd B et al. 2019); rarely on the lower extremities.

Clinical features
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Large (2.0-20 cm in diameter) and deep-reaching, sharply defined, painful ulcer penetrating the subcutis and muscles in immunocompromised patients (especially those infected with HIV).

Differential diagnosis
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Bacterial ulcers

Fournier gangrene(Gangraena acuta genitalium)

Internal therapy
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Successes have been described with the preparation Valganciclovir, also with Foscarnet and Ganciclovir.

Literature
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  1. Class U et al (2008) Skin infections in organ transplant patients. JDDG 6: 98-105Drozd
    B et al (2019) Cutaneouscytomegalovirus
    manifestations, diagnosis, and treatment: a review. DermatolOnline
    J 25:13030/qt84f936cp.
  2. Lambert EM et al (2004) Cytomegalovirus ulcer. Arch Dermatol 140: 1199-2101

Incoming links (1)

Anal fissure;

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020