Synonym(s)
Apo-1; Fas
DefinitionThis section has been translated automatically.
Cells: CD4+, CD8+ T cells, B cells, variable also on monocytes and granulocytes, tissue
Structure: Transmembrane glycoprotein (40-50 kDa)
Note: CD95 (also known as APO-1 or Fas) belongs to the tumor necrosis factors and is mainly responsible for apoptosis (programmed cell death). The ligand of Fas is FasL(CD178). CD95 is upregulated when cells are activated.
Application: FACS, IHC (P) (G)
(see below) Cluster of differentiation
LiteratureThis section has been translated automatically.
- Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer publishing house Berlin-Heidelberg p. 26-33.
Prof. Dr. med. Peter Altmeyer