Synonym(s)
Macrosialine
DefinitionThis section has been translated automatically.
Acronym for"Cluster of differentiation 68".
Note: CD68 labels monocytes, macrophages, mast cells, "plasmacytoid T cells", myeloid progenitor cells. The antibody is useful in the diagnosis of acute and chronic myeloid leukemia (AML and CML).
Structure: 110 kDA
Note: CD68 is a lysosomal antigen: all lysosome-rich cells (granular cells) are CD68+: for example cells of granular cell tumour. Myxofibrosarcoma also shows a high expression of CD68.
LiteratureThis section has been translated automatically.
- Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer Publishing House Berlin-Heidelberg p. 28.
Prof. Dr. med. Peter Altmeyer