Cayenne pepper extract

Rubefaciency based on capsacinoids calculated as capsaicin. Ingredients of the extract are: capsacinoids, carotenoids, flovonoids, fatty oil.

After topical application, capsaicin selectively depolarizes sensory nozic receptors and releases neuropeptides that induce neurogenic inflammation in the extracellular space with plasma extravasation, inflammation and hyperalgesia. The consequences of the described stimulation are an emptying of the storage and a prevention of the new synthesis of substance P.
Repeated applications of capsaicin lead to nervous "desensitization", which is accompanied by anti-inflammatory and antinoceptive effects.

Rheumatic diseases, postherpetic neuralgia, diabetic polyneuropathy, arthritic complaints, degenerative joint diseases, ischialgia, contusions.

Remarks. Burns on open areas. Do not use on eyes or mucous membranes!

In rare cases a hypersensitivity reaction of the skin may occur (urticarial exanthema). More often, a burning and stinging pain, redness, heat development, coughing and sneezing irritation when inhaled occurs. Prolonged use may cause damage to sensitive nerves, skin irritation and contact dermatitis.

Dosage: 0,02 to 0,05 % capsacinoids as semi-solid preparation, 0,05 to 0,1 % in plasters correspond to 10 to 40 ug/cm² capsacinoids. It is recommended to apply a 0.075% ointment thinly 2 to 3 times a day.
4% as ointment or 5% as liniment should be massaged into the affected area several times a day.
The duration of application should not exceed two days. Before using again at the same application site, a break of two to four weeks is recommended.

Hypersensitivity to the active substance, application to the eye and mucous membranes, inflammatory skin diseases, open wounds; pregnancy, lactation.

Advel® Thermobalsam cream, Capsamol® ointment, Finalgon® Capsicum cream, rhemaumed® ointment, Thermo-Bürger® cream, Dolenon®, Gothaplast Rheumamed® AC heat plaster

1. Loew D (2012) in Beer A M et al [Ed.] Leitfaden Naturheilverfahren für die ärztliche Praxis, Urban und Fischer Verlag S 187.