Calcinosis metastatica; calcifying uremic arteriolopathy; metastatic calcinosis E83.5

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

calcinosis circumscripta; calcinosis cutis

Definition
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Deposition of calcium salts due to a disturbance in the calcium and/or phosphate metabolism with simultaneous local factors favouring precipitation of calcium salts.

Occurrence/Epidemiology
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In primary and secondary hyperparathyroidism, chronic kidney disease, vitamin D-hypervitaminosis, destructive bone diseases, multiple myeloma (see also paraproteinemia, skin changes), sarcoidosis, the milk-alkali-syndrome and in various other diseases. Drugs (lithium, coumarins). Chronic kidney diseases and dialysis are the most common causes.

Clinical features
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Symmetrical or linearly arranged, painful, hard, white papules, also plaque or nodular lesions. Risk of ulceration with poor healing tendency.

General therapy
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Treatment of the underlying disease. Diet low in calcium and/or phosphate.

External therapy
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Treatment of circumscribed calcinoses, see below Calcinosis circumscripta.

Cave! Delayed wound healing and tendency to ulceration even in small wounds (patient education)!

Note(s)
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The term calcinosis metastatica is used synonymously with the term calcinosis metabolica.

Literature
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  1. Allmendinger M et al.(2014) Calcinosis metastatica in secondary hyperparathyroidism in Vit-D deficiency. Act Dermatol 40: 350-352

Incoming links (1)

Vitamin d hypervitaminosis;

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Last updated on: 29.10.2020