DefinitionThis section has been translated automatically.
Organic mercury compound, which is one of the most common contact allergens ( allergy) worldwide. No longer used as a disinfectant in Germany (Ammann PM et al. 2018).
Field of application/useThis section has been translated automatically.
Preservative in vaccines, eye drops, contact lens solutions and other external agents.
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Undesirable effectsThis section has been translated automatically.
Contact allergy, acute urticaria, facial edema, laryngeal edema, bronchospasm.
Note(s)This section has been translated automatically.
Potentially possible rashes on thiomersal used as a preservative in some vaccines are so rare that even if the epicutaneous test for thiomersal is positive, vaccination with the preparation is still possible. The vaccination is almost always tolerated without problems. Nevertheless, the search for an alternative vaccine which is not substituted by thiomersal is recommended.
Cosmetics: Thiomersal can be used in cosmetic formulations under the INCA name "Thiomersal". The use of thiomersal is not recommended!
LiteratureThis section has been translated automatically.
- Ammann PM et al (2018) Disinfectants. Allergo J 27:16-18
- Clarkson TW et al (2003) The toxicology of mercury--current exposures and clinical manifestations. N Engl J Med 349: 1731-1737
- Gille J, Goerz G (1992) Thiomersal: A common contact allergen. Z. Skincr. 67:1049-1054
- Wollenberg A, Vogel S, Renner ED (2010) Vaccinations for neurodermatitis and other chronic inflammatory skin diseases. dermatologist 61: 985-993
Prof. Dr. med. Peter Altmeyer