CCL5

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 28.11.2021

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Synonym(s)

normal T-expressed and secreted; RANTES; regulated upon activation

General information
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Proinflammatory cytokine and basic chemokine (β-chemokine) with chemotactic effect on various inflammatory cells (monocytes, T lymphocytes, NK cells, basophilic and eosinophilic granulocytes and dendritic cells).

Physiological ligand of the HIV-1 co-receptors CCR3, CCR4 and CCR5 (see below chemokine receptors).

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Last updated on: 28.11.2021