Benzoic acid
Synonym(s)
benzoic acid; E210
DefinitionThis section has been translated automatically.
Antiseptic, disinfecting and as a preservative(preservatives) widely used substance. The salts of benzoic acid are called benzoates.
Field of application/useThis section has been translated automatically.
As a preservative for food (0.1-0.25%; for fish and shellfish up to 0.4%)
Naturally occurring benzoic acid and benzoates are skin constituents of the benzoic resin(benzoin), which is derived from various types of wood. Styrax species. Benzoic acid is also found in plums, cinnamon, cloves, aniseed, raspberries and cranberries.
IndicationThis section has been translated automatically.
Superficial skin infections.
Standard concentrationThis section has been translated automatically.
Up to 5% in water absorbing ointments (absorption bases), hydrophilic ointments, hydrophobic creams (W/O emulsion ointments), hydrophilic creams (O/W emulsion ointments), carmellose gel, hydroxyethyl cellulose gel.
Undesirable effectsThis section has been translated automatically.
Allergic reactions have been observed sporadically; contact allergies are somewhat more common in the pharmaceutical industry. Frequency of intolerance reactions in the resident population is unknown; higher risk in patients with chronic urticaria, bronchial asthma, analgesic intolerance (10-20%).
IncompatibilityThis section has been translated automatically.
Neutral or alkaline solutions.
LiteratureThis section has been translated automatically.
- Jäger L, Wüthrich B (1997) Food allergies and intolerances. Gustav Fischer, Ulm Stuttgart Jena Lübeck, S. 165-166
- Kumar A et al (2003) Synthesis of some newer derivatives of 2-amino benzoic acid as potent anti-inflammatory and analgesic agents. Bioorg Med Chem 11: 5281-5291