Department Internal medicine

TP53 Gene

TP53 Gene Definition The TP53 gene (TP53 is the acronym for Tumor Protein 53) is a tumor suppressor gene. In humans, the TP53 gene is located on the short arm of chromosome 17 (17p13.1). The gene comprises 20 kb, with a non-coding exon 1 and a very long first intron of 10 kb. TP53 orthologs have ...