Travel thrombosisI82.8

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Coach class syndrome; Traveler`s thrombosis; Traveller`s thrombosis

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DefinitionThis section has been translated automatically.

Occurrence of a phlebothrombosis of the lower extremity with/without pulmonary embolism complications in a temporal connection with a journey of many hours in a predominantly sitting position in persons who had no evidence of acute venous thromboembolism before the start of the journey.

ClassificationThis section has been translated automatically.

Risk groups:
  • Risk group 1 (low risk): Every journey of many hours in a predominantly seated position.
  • Risk group 2 (medium risk): In addition to travelling for several hours in a seated position, there are also: pregnancy or postpartum phase.
  • Alternative: Presence of at least 2 of the following factors:
    • Age > 60 years
    • Clinically relevant heart disease
    • Proven thrombophilia or familial thrombosis
    • ovulation inhibitors, postmenopausal hormone replacement therapy
    • Adiposity (BMI > 30)
    • Desiccation.
  • Risk group 3 (high risk):
    • History of thrombophilia, even a long time ago
    • Manifest malignant or other serious illness
    • Joint immobilization of a lower extremity
    • Recent surgery with high risk of thrombosis.

Occurrence/EpidemiologyThis section has been translated automatically.

There are no reliable figures on the frequency of travel thrombosis. It is estimated that the prevalence on long-haul flights (> 4 hours) is 1:4,500 -6,000 passengers. The risk of post-thrombotic pulmonary embolism is also increased compared to a control collective.

Possible risks are a known thrombophilia, relevant varicosis, previous thromboses, diabetes mellitus, kidney disease, pregnancy or the use of contraceptives.

ProphylaxisThis section has been translated automatically.

  • Risk group 1: Movement exercises (bouncing feet, isometric exercises, repeated standing up, ample fluid intake (reduction of diuretic stimulants: coffee, alcohol, tea), avoidance of sedatives and hypnotics during the trip (!)
  • Risk group 2: In addition to the measures of risk group 1: wearing of lower leg stockings of compression class 1 or adapted to the degree of CVI. In individual cases (e.g. pregnancy or thrombophilia) treatment with low molecular weight heparin s.c.
  • Risk group 3: In addition to the measures described above under risk group 1 or 2: Drug prophylaxis (see c. Injections of low-molecular-weight heparin 2 hours before departure (once a day for round trips).

LiteratureThis section has been translated automatically.

  1. Ansell JE (2001) Air travel and venous thromboembolism--is the evidence in? N Engl J Med 345: 828-829
  2. Belcaro G et al (2001) Venous thromboembolism from air travel: the LONFIT study. Angiology 52: 369-374
  3. Brown S, disciple M (2003) Travel thrombosis. The dermatologist 54: 518-523
  4. Lapostolle F et al (2001) Severe pulmonary embolism associated with air travel. N Engl J Med 345: 779-783
  5. Mendis S et al (2002) Air travel and venous thromboembolism. Bull World Health Organ 80: 403-406
  6. Partsch H et al (2001) Travel thrombosis 2001. consensus paper. Phlebology 30: 101-103

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Last updated on: 29.10.2020