Thrombo(cyto)pathia - Altmeyers Encyclopedia - Department Vascular medicine

Definition
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Disturbances in platelet function, whereby the number and/or function of the platelets may be disturbed. The bleeding time is prolonged, clinically petechial bleeding ( purpura) occurs.

Classification
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A distinction is made between congenital and acquired forms:

Congenital thrombocytopathies:
- Thrombasthenia, Bernard-Soulier syndrome, Willebrand v. Jürgens disease, May-Hegglin anomaly. A special form are defects with reduced availability of thrombocyte factor 3 ( Thrombopathia haemophilica).
Acquired or secondary thrombocytopathies:
- In the context of various underlying diseases (leukaemia, renal insufficiency, paraproteinemia) or as a result of taking antiplatelet medication (reversible).