DefinitionThis section has been translated automatically.
Prostavasin is a prostaglandin E1 analogue. It is used in the treatment of stage III and IV peripheral arterial occlusive disease (I73.9), the main mechanism of which is vasodilation. However, prostavasin also acts by inhibiting platelet aggregation by activating the specific prostaglandin receptors of the platelets.
Dosage and method of useThis section has been translated automatically.
2x 40 ug in 250 ml NaCl over 2 hours i.v.
An intra-arterial administration is possible. Dosage: 1 x 10-20 ug in 50 ml NaCl over 60 to 120 minutes.
Cave: renal insufficiency. With a creatinine value of more than 1.5 2 x 20 ug i.v., then 2 x 40 ug i.v. Contraindication for liver disease.
PreparationsThis section has been translated automatically.
alprostadil®
LiteratureThis section has been translated automatically.
- HA Neumann (2014) The coagulation system. ABW-Scientific Publisher GmbH Berlin
Prof. Dr. med. Peter Altmeyer