Polyarteritis nodosa systemic Images
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Polyarteritis nodosa, systemic, multiple, chronically dynamic, since 2 years steadily increasing, progressive in size, localized on the extensor side of the lower leg, disseminated, 0.5-4.0 cm large, very painful, flatly elevated, red and brown plaques, nodules (iceberg phenomenon) as well as very painful ulcers.


Polyarteritis nodosa, systemic. 37-year-old woman; ulcerated nodule in typical localization, highly painful, existing for 6 months.

Polyarteritis nodosa, systemic. close-up: Ragged, deep-reaching ulcer covered with fibrin.


Polyarteriitis nodosa, systemic. excisional biopsy from an infiltrated node reaching into the subcutaneous fatty tissue. in the tissue block on the right a medium caliber artery with thrombus.

Polyarteritis nodosa, systemic. Thrombosed vessel at the corium-subcutaneous junction.

Polyarteritis nodosa, systemic section of the above figure: Fresh thrombus in the vascular lumen, perivascularly localized edema with sparse inflammatory infiltrates.

Polyarteriitis nodosa, systemic. further detail: Medium caliber artery with fresh central thrombus; the vessel wall is loosened with sparse inflammatory infiltrates of lymphocytes and neutrophil granulocytes.