Synonym(s)
Marjolin`s ulcer; Marjolin ulcer
DefinitionThis section has been translated automatically.
Ulcer decaying, malignant tumour on the lower leg (e.g. spinocellular carcinoma, basal cell carcinoma, malignant melanoma, Kaposi's sarcoma, etc.) which may imitate an ulcer of a different origin. It is not always possible to clarify whether it is a tumour that primarily developed on intact skin or whether it is a complicated malignoma at the base of a long-term existing leg ulcer (> 3 years). According to the initial description, a Marjolin ulcer is a squamous cell carcinoma or basal cell carcinoma on the floor of a primarily non-neoplastic leg ulcer.
Occurrence/EpidemiologyThis section has been translated automatically.
Men are affected in a ratio of 2.5:1.0 compared to women. Average age of the disease: 75 years. Ulcer diseases (mostly venous leg ulcers) usually persist for more than 25 years.
You might also be interested in
Clinical featuresThis section has been translated automatically.
Therapy-resistant ulcer cruris with mostly excessive red granulation tissue and a raised, firm edge wall.
Differential diagnosisThis section has been translated automatically.
S.u. Ulcus cruris.
TherapyThis section has been translated automatically.
S.u. of the respective underlying disease.
LiteratureThis section has been translated automatically.
- Combemale P et al (2007) Malignant transformation of leg ulcers: a retrospective study of 85 cases. JEADV 21: 935-941
- Marjolin JN (1828) Ulcère. In: Dictionnaire de Médicine. Adelon NP ed. Mugs, Paris p. 31-50
Recommended articles
Incoming links (1)
Venous leg ulcer;Outgoing links (7)
Basal cell carcinoma (overview); Kaposi's sarcoma (overview); Leg ulcer; Marjolin ulcer; Melanoma cutaneous; Squamous cell carcinoma of the skin; Venous leg ulcer;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer