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Mondor's diseaseI82.1

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 18.09.2022

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Synonym(s)

Iron wire phlebitis; Mondor disease; Mondor phlebitis; Mondor syndrome; phlébite en cordon de la paroi thoracique; phlébite en fil de fer; sclerosing periphlebitis of the chestwall; sclerosing thrombophlebitis; String-shaped phlebitis

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HistoryThis section has been translated automatically.

Mondor, 1939

DefinitionThis section has been translated automatically.

Rare, little inflammatory, superficial, peculiarly wire-like hard, strand-like, moderately painful phlebitis in the thoracoepigastric veins. Also possible in other localizations, such as the shaft of the penis in men. Mondor's disease is considered a special form of thrombophlebitis saltans.

EtiopathogenesisThis section has been translated automatically.

Pathogenetically it is a circumscribed, sclerosing thrombophlebitis of the subcutaneous thoracic veins of unknown cause. Described in connection with trauma, operations, infections, exertion, coagulation disorders. Cases after thermal ablation of varices have been observed.

ManifestationThis section has been translated automatically.

Occurs mainly in women between 30 and 60 years of age.

LocalizationThis section has been translated automatically.

Lateral chest wall, anterior axillary line. String-shaped superficial phlebitids also occur in other regions, e.g. on the upper lid, the extremities and the prepuce.

Clinical featuresThis section has been translated automatically.

Straight running, 0.2-0.3 cm thick, several centimetres long, hard, not or hardly reddened strand on the chest wall or in the armpit. Usually only minor subjective complaints: feeling of tension during movements and low sensitivity of the lateral thorax and the anterior axillary line. Spontaneous regression after a few weeks. After healing in the area of the previous lesion, sometimes persistent pressure pain.

HistologyThis section has been translated automatically.

Sclerosing endophlebitis (giant cell vasculitis) with complete or partial closure of the vascular lumina by thrombi. Frequent detection of giant cells.

Differential diagnosisThis section has been translated automatically.

Sclerosing lymphangitis.

TherapyThis section has been translated automatically.

Clarification and rehabilitation of any underlying tumour. Otherwise, the patient is informed about the relative harmlessness of the findings, which usually disappear within a few weeks. Anticoagulant ointments such as heparin or hirudoid ointment can be used as a support.

Some authors recommend anticoagulation with a low molecular weight heparin (e.g. 2.5mg Fondaparinux 1x/day for 45 days)

Progression/forecastThis section has been translated automatically.

Spontaneous healing after weeks to months.

LiteratureThis section has been translated automatically.

  1. Bartolo M, Bartolo M, Amoroso A, Bonomo L (1993) La malattia di Mondor. Osservazioni su 22 casi. Recenti Prog Med 84: 737-741
  2. Catania S et al (1992) Mondor's disease and breast cancer. Cancer 69: 2267-2270 Diamantopoulos EJ et al. (1999) Giant-cell arteritis presenting as Mondor's disease. Ann Internal Med 130: 78-79
  3. Holle-Robatsch S et al (2001) Mondor phlebitis associated with hepatitis C. Vasa 30: 297-298
  4. Mondor H (1939) Tronculite souscutanée subaiguë de la paroi thoracique antéro-laterale. Mem Acad Chir 65: 1271-1278
  5. Paes E, Rahmer H, Mitic B (1985) Mondor's disease. A casuistic contribution. Phlebol u Proctol 14: 133-134
  6. Zerweck C et al (2014) Morbus Mondor after endovenous laser ablation of the magna saphenous vein - a rare complication of endothermic varicose vein therapy. Vasomed 26: 215-216

Authors

Last updated on: 18.09.2022

Author: Prof. Dr. med. Peter Altmeyer