Lymphedema, type meige Q82.0

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

late-onset; lymphedema; Lymphedema; lymphedema late-onset; lymphedema praecox familial; Maladie de Meige; Meige's disease; Meige\'s disease; Meige syndrome; Trophodema; Trophodema type Meige; Type Meige

History
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Meige, 1889

Definition
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Genetically determined primary lymphedema corresponding to lymphedema, type Nonne-Milroy with further associated symptoms and later manifestation

Etiopathogenesis
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Unknown.

Manifestation
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Puberty. Women are affected twice as often as men.

Clinical features
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  • According to the lymphedema, type Nonne-Milroy, s. there.
  • In addition: short stature, mental retardation, hypogenitalism, ptosis of the eyelids, recurrent intrahepatic cholestasis, obesity in the area of the breeches; rarely additional infestation of the genitals, upper extremities, face, larynx and pleura (effusions).
  • Congenital anomalies: partial membranous syndactylia of the toes, distichiasis (double row of eyelashes); myopia; ptosis; yellow nails; extradural cysts and/or vertebral anomalies; cerebrovascular malformations; sensoneural hearing loss; cleft palate. Bronchiectasis.

Therapy
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Literature
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  1. Figueroa AA, Pruzansky S, Rollnick BR (1983) Meige disease (familial lymphedema praecox) and cleft palate: report of a family and review of the literature. Cleft palate J 20: 151-157
  2. Meige H (1898) Dystrophy oedematose hereditaire. La presse médicale (Paris) 6: 341-343
  3. Meige H (1889) Le trophoedème chronique héréditaire. Nouv iconogr Salpêtrière, Paris, 12: 453-480
  4. Ho WL et al (2003) Radiological features of late-onset lymphoedema in Noonan's syndrome. Pediatric radiol 33: 200-202
  5. Samlaska CP (2002) Congenital lymphedema and distichiasis. Pediatric Dermatol 19: 139-141
  6. Tammer ME et al (2002) Surgical therapy of scrotal edema in elephantiasis congenita hereditaria (Meige type). Urologist A 41: 493-495
  7. Wheeler ES et al (1981) Familial lymphedema praecox: Meige's disease. Plast Reconst Surgery 67: 362-364

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Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020