Synonym(s)
back leg of a healthy woman; Column leg; Fat bone; Fat syndrome painful; Lipedema; Lipidosis; painful fat syndrome; Painful fat syndrome; Painful fatty syndrome; Painful lipedema syndrome of the lower legs; zonal obesity
HistoryThis section has been translated automatically.
Allen and Hines, 1940
DefinitionThis section has been translated automatically.
Clinical syndrome characterized by proliferation of subcutaneous fatty tissue and orthostatic leg edema, accompanied by a fat distribution disorder, especially in the thighs and lower legs.
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EtiopathogenesisThis section has been translated automatically.
Unclear; family disposition is described. The disease seems to start with an increased capillary filtration through the loose fatty tissue structure. Edema formation leads to secondary occlusion of capillary vessels with reduction of lymph transport.
ManifestationThis section has been translated automatically.
Usually begins after puberty. Women are about 100 times more frequently affected than men.
LocalizationThis section has been translated automatically.
Hips, thighs and lower legs, feet usually free.
Clinical featuresThis section has been translated automatically.
Symmetrical, coarse, indentable swelling of the legs, which increases with prolonged orthostatic load, with diffuse pain or pain due to pressure, especially in the area of the tibial crest. Supramalleolar collar (fat muff). Typical are swollen thighs and lower legs with slender feet!
LaboratoryThis section has been translated automatically.
Occasionally hyperlipoproteinemia.
Differential diagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
Manual lymphatic drainage or intermittent compression therapy using equipment (e.g. lymphatic mat or hydroven), depending on the lymphedema. Compression stockings as permanent treatment.
Progression/forecastThis section has been translated automatically.
Slowly progressive course.
LiteratureThis section has been translated automatically.
- Allen EV, Hines EA (1940) Lipedema of the legs. Proc. Mayo Clin 15: 184-187
- Hines EA, Allen EV (1951) Lipedema of legs: a syndrome characterized by fat legs and oedema. Ann Intern Med (Philadelphia) 34: 1243-1250
- Macdonald JM et al (2003) Lymphedema, lipedema, and the open wound: the role of compression therapy. Surg Clin North Am 83: 639-658
- Monnin-Delhom ED et al (2002) High resolution unenhanced computed tomography in patients with swollen legs. Lymphology 35: 121-128
- Tiwari A et al (2003) Differential diagnosis, investigation, and current treatment of lower limb lymphedema. Arch Surgery 138: 152-161
- Wienert V et al (1991) The lipedema. dermatologist 42: 484-486
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Incoming links (7)
Adiposis dolorosa; Adiposity, zonal; Column leg; Fat bone; Fat syndrome, painful; Lipidosis; Painful fat syndrome;Outgoing links (9)
Adiposis dolorosa; Chronic venous insufficiency (overview); Compression stocking medical; Compression therapy; Dermatosclerosis; Lymph drainage; Lymphedema (overview); Phlebödem; Scleroedema adultorum;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer