Doak

Direct oral anticoagulants, DOAK for short, is the generic term for a group of anticoagulant drugs that act directly against certain coagulation factors and can be taken orally. Since these substances have only been on the market for a few years, the term "new oral anticoagulants" or "non-vitamin K-dependent anticoagulants" NOAKs is used alternatively.

Anticoagulation by direct inhibition of factor Xa or thrombin. This results in a faster onset of action compared to vitamin K antagonists. There are currently 4 active ingredients available on the German market:

• Apixaban
• Edoxaban
• Dabigatran
• Rivaroxaban

Details on the different active ingredients can be found under the respective keywords.