Disorders of the coagulation system (haemorrhagic diathesis) D69.-

Disturbances of the coagulation system can be caused by

• of the platelets,
• the plasma factors and
• the vessels may be tempted.

Platelet diseases and their classification at a glance:

• Platelet pennies
  • Autoimmunological
  • Drug toxicity
  • for splenomegaly
  • for disseminated intravascular coagulation
  • Thrombotic-thrombocytopenic purpura (Moschcowitz syndrome)
  • EDTA-induced
  • Heprarin-induced
  • In the context of malignancies, e.g. leukaemias
• Platelet dysfunction
  • Defects in the adhesion capacity
  • von Willebrand-Jürgens Syndrome
  • Defects of the aggregation ability (thrombasthenia Glanzmann-Nägeli)
  • Bernard-Soulier syndrome
  • Defects of the release reactions in the activation process
  • Sticky-platelet syndrome
  • acquired functional disorders in uremia, liver diseases
  • Drug-induced.

1. HA Neumann (2014) The coagulation system. ABW-Wissenschaftsverlag GmbH Berlin S. 131.