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Sitosterol

Authors:Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 20.10.2022

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Synonym(s)

3beta-sitosterol; CAS No 83-46-5; sitosterol

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DefinitionThis section has been translated automatically.

Widespread phytosterol which as a plant steroid is very closely related to cholesterol. Beta-Sitosterol belongs together with Campesterol and Stigmasterol to the most common phytosterols of plants (see below sterols).

OccurrenceThis section has been translated automatically.

This phytosterol can be detected in cereal germs, soybeans, Urtica species (stinging nettle), Cucurbita species (cucurbits), etc.

EffectsThis section has been translated automatically.

Reduces the absorption of cholesterol from the gastrointestinal tract (previously used as a lipid reducer). Sitosterol also reduces the effect of dihydrotestosterone and interacts with the sex hormone binding globulin (SHGB). In this respect, sitosterol was previously used as a remedy for benign prostate adenoma (see also Urticae radix).

LiteratureThis section has been translated automatically.

  1. Miras-Moreno B et al. (2016) Bioactivity of phytosterols and their production in plant in vitro cultures. J Agric Food Chem 64:7049-7058.
  2. Valitova JN et al.(2016) Plant Sterols: Diversity, Biosynthesis, and Physiological Functions. Biochemistry (Mosc) 81:819-834.

Authors

Last updated on: 20.10.2022

Authors: Prof. Dr. med. Peter AltmeyerProf. Dr. med. Martina Bacharach-Buhles