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Rhamni purshianae cortex
Synonym(s)
DefinitionThis section has been translated automatically.
Phytotherapeutically used bark of the American buckthorn.
Quality is defined in the European Pharmacopoeia (Ph. Eur.)
HMPC monograph: well-established use: Internal: short-term treatment of constipation, 1 week
ESCOP monograph: short-term treatment of constipation.
Commission e-monograph: constipation
Cosmetics: Rhamnus purshiana bark extract (INCI)
IngredientsThis section has been translated automatically.
Efficacy-determining ingredients: numerous hydroxyanthracene glycosides, especially of the aloe emodin type, as well as glycosides of emodin (of which 80-90% are C-glycosides of the aloe type, so-called cascarosides); also tanning agents(tannins) According to ph.
EffectsThis section has been translated automatically.
Laxative, anti-absorptive.
Field of application/useThis section has been translated automatically.
Indication (Committee E): Constipation
DosageThis section has been translated automatically.
20-30mg hydroxyanthracene derivatives calculated as cascaroside A. Duration of intake 1-2 weeks.
Undesirable effectsThis section has been translated automatically.
Cramp-like gastrointestinal disorders, disorders of water and electrolyte balance, especially potassium loss with subsequent cardiac function and muscle weakness if cardiac glycosides, diuretics and adrenal steroids are taken at the same time. Possibly albuminuria, hematuria, reversible pigmentation of the intestinal mucosa = pseudomelanosis coli.
ContraindicationThis section has been translated automatically.
Contraindications: ileus, acute inflammatory bowel disease, unexplained abdominal pain, severe dehydration, pregnancy and breastfeeding.
InteractionsThis section has been translated automatically.
Enhancement of the effect of cardiac glycosides with prolonged use due to the resulting potassium deficiency, also change in the effect of antiarrhythmic drugs.
Cave also: thiazide diuretics, adrenal steroids, licorice root - increase potassium losses.
Recipe(s)This section has been translated automatically.
Tea: Mix one teaspoon of the dried, crushed bark with cold water per cup and leave to infuse overnight. Boil the tea briefly before drinking.
Or: Pour boiling water over 0.5 g of the finely chopped drug, strain after 10-15 minutes - drink at night, before going to bed.
Face mask (seborrhoeic skin): Mix a handful of buckthorn bark with a liter of water and boil for half an hour. Apply a compress with the liquid to the soap-cleansed facial skin for several minutes.
Trade namesThis section has been translated automatically.
Legapas® film-coated tablets or drops.
Note(s)This section has been translated automatically.
Not for children <12 years
LiteratureThis section has been translated automatically.
- Koyama J et al.(2001) Inhibitory effects of anthraquinones and bianthraquinones on Epstein-Barr virus activation. Cancer Lett 170:15-18.
- https://arzneipflanzenlexikon.info/faulbaum.php
- https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-rhamnus-purshiana-dc-cortex-revision-1_en.pdf
- Blaschek W (2015) Wichtl tea drugs and phytopharmaceuticals. A handbook for practice. Wissenschaftliche Verlagsgesellschaft Munich. S 548-549