Psoralene

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 17.01.2025

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Definition
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Furanocoumarin derivatives, tricyclic ring systems in which the furan ring is linearly linked to the coumarin. The psoralens, as linear 7,6-furanocoumarins, are photosensitizing. PUVA therapy with 8-methoxypsoralen(ammoidin) is based on their photosensitizing properties (see PUVA). Psoralens occur naturally in many Rutaceae (rue plants), Apiaceae (umbellifers) and Fabaeceae (legumes).