Psoralene

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 23.02.2021

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Definition
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Furanocoumarin derivatives, tricyclic ring systems in which the furan ring is linearly linked to the coumarin. The psoralens, as linear 7,6 - furanocoumarins are photosensitizing. PUVA therapy with 8-methoxypsoralen(ammoidine) is based on their photosensitizing capacity (cf. PUVA). Psoralens occur naturally in many Rutaceae, Apiaceae and Fabaeceae.