Lycopi herba

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 21.11.2024

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Synonym(s)

Herba Lycopi; Wolfstraw

Definition
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Lycopi herba, also known as wolf's bane, is a drug made from the crushed plant, from fresh plant juice and is used in herbal medicinal products for the treatment of mild forms of hyperthyroidism and mastodynia.

Commission E-monograph: Mild hyperthyroidism with vegetative-nervous disorders, a feeling of tension and pain in the mammary gland (mastopathy)

Empirical medicine: premenstrual syndrome

Ingredients
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Wolfstraw contains 0.2% essential oil, flavonoids, fluorides, lithospermic acid as well as hydroxycinnamic acid derivatives (e.g. ferulic acid), caffeic acid derivatives and rosemary acid.

Effects
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Wolfstraw reduces the level of prolactin in the body, inhibits the peripheral deodorization of T4 and also has antithyrotropic and antigonadotropic effects.

Field of application/use
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Wolfstraw is used for a mild form of hyperthyroidism with autonomic nervous disorders and mastodynia(Commission E).

Dosage
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The daily dose is between 1.0 and 2.0 g. The drug is usually taken in the form of tea infusions, aqueous-ethanolic extracts or as fresh plant juice.

Undesirable effects
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In very rare cases, an enlargement of the thyroid gland can occur with a very high dosage or as part of long-term therapy. Wolfstraw should only be discontinued very slowly, otherwise the symptoms may become worse.

Contraindication
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In case of a known hypothyroidism or a struma nodosa without dysfunction, it should not be taken.

Interactions
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There are no known interactions with other substances. A parallel intake of thyroid hormones should be avoided.

Note(s)
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To avoid rebound phenomenon, the intake should be started and stopped slowly.

Lycopus preparations interfere with thyroid diagnostics with radio-isotopes.

Literature
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  1. Ghosh S et al. (2017) New insights into the ameliorative effects of ferulic acid in pathophysiological conditions. Food Chem Toxicol doi: 10.1016/j.fct.2017.02.028.
  2. Mancuso C et al.(2014) Ferulic acid: pharmacological and toxicological aspects. Food Chem Toxicol 65:185-195.
  3. Klepacka J et al. (2006) Ferulic acid and its position among the phenolic compounds of wheat. Crit Rev Food Sci Nutr 46:639-647.
  4. Mathew S et al. (2004) Ferulic acid: an antioxidant found naturally in plant cell walls and feruloyl esterases involved in its release and their applications. Crit Rev Biotechnol 24(2-3):59-83.
  5. Sgarbossa A et al. (2015) Ferulic acid: A Hope for Alzheimer's Disease Therapy from Plants. Nutrients 7:5764-5782.
  6. Staniforth V et aL.(2012) Ferulic acid, a phenolic phytochemical, inhibits UVB-induced matrix metalloproteinases in mouse skin via posttranslational mechanisms. J Nutr Biochem 23:443-451.
  7. Schilcher H (2016) In: Leitfaden Phytotherapie, Urban & Fischer Verlag Munich, pp. 345 f.
  8. Wenigmann M.(2017) Phytotherapy medicinal drugs phytopharmaceuticals application. Urban & Fischer: 5.123 Wolfstrappkraut (Lycopi herba) p 217-218.

Incoming links (2)

Wolfstrapp, meaner; Wolfstraw;