Synonym(s)
DefinitionThis section has been translated automatically.
Lycopi herba, also known as wolf's bane, is a drug made from the crushed plant, from fresh plant juice and is used in herbal medicinal products for the treatment of mild forms of hyperthyroidism and mastodynia.
Commission E-monograph: Mild hyperthyroidism with vegetative-nervous disorders, a feeling of tension and pain in the mammary gland (mastopathy)
Empirical medicine: premenstrual syndrome
IngredientsThis section has been translated automatically.
Wolfstraw contains 0.2% essential oil, flavonoids, fluorides, lithospermic acid as well as hydroxycinnamic acid derivatives (e.g. ferulic acid), caffeic acid derivatives and rosemary acid.
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EffectsThis section has been translated automatically.
Wolfstraw reduces the level of prolactin in the body, inhibits the peripheral deodorization of T4 and also has antithyrotropic and antigonadotropic effects.
Field of application/useThis section has been translated automatically.
Wolfstraw is used for a mild form of hyperthyroidism with autonomic nervous disorders and mastodynia(Commission E).
DosageThis section has been translated automatically.
The daily dose is between 1.0 and 2.0 g. The drug is usually taken in the form of tea infusions, aqueous-ethanolic extracts or as fresh plant juice.
Undesirable effectsThis section has been translated automatically.
In very rare cases, an enlargement of the thyroid gland can occur with a very high dosage or as part of long-term therapy. Wolfstraw should only be discontinued very slowly, otherwise the symptoms may become worse.
ContraindicationThis section has been translated automatically.
In case of a known hypothyroidism or a struma nodosa without dysfunction, it should not be taken.
InteractionsThis section has been translated automatically.
There are no known interactions with other substances. A parallel intake of thyroid hormones should be avoided.
Note(s)This section has been translated automatically.
To avoid rebound phenomenon, the intake should be started and stopped slowly.
Lycopus preparations interfere with thyroid diagnostics with radio-isotopes.
LiteratureThis section has been translated automatically.
- Ghosh S et al. (2017) New insights into the ameliorative effects of ferulic acid in pathophysiological conditions. Food Chem Toxicol doi: 10.1016/j.fct.2017.02.028.
- Mancuso C et al.(2014) Ferulic acid: pharmacological and toxicological aspects. Food Chem Toxicol 65:185-195.
- Klepacka J et al. (2006) Ferulic acid and its position among the phenolic compounds of wheat. Crit Rev Food Sci Nutr 46:639-647.
- Mathew S et al. (2004) Ferulic acid: an antioxidant found naturally in plant cell walls and feruloyl esterases involved in its release and their applications. Crit Rev Biotechnol 24(2-3):59-83.
- Sgarbossa A et al. (2015) Ferulic acid: A Hope for Alzheimer's Disease Therapy from Plants. Nutrients 7:5764-5782.
- Staniforth V et aL.(2012) Ferulic acid, a phenolic phytochemical, inhibits UVB-induced matrix metalloproteinases in mouse skin via posttranslational mechanisms. J Nutr Biochem 23:443-451.
- Schilcher H (2016) In: Leitfaden Phytotherapie, Urban & Fischer Verlag Munich, pp. 345 f.
- Wenigmann M.(2017) Phytotherapy medicinal drugs phytopharmaceuticals application. Urban & Fischer: 5.123 Wolfstrappkraut (Lycopi herba) p 217-218.