Lawson

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 29.10.2020

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Synonym(s)

2-hydroxy-1,4-naphthalenedione; 2-hydroxy-p-naphthoquinone; CAS number: 83-72-7; Lawsone (engl.)

Definition
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Red, naphthoquinone dye from the group of ketones and naphthols, which is obtained naturally in a concentration of 1-2% from young branches and leaves of the dyer's shrub (also henna shrub), Lawsonia inermis.

Note(s)
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For allergic skin reactions that appear shortly after the application of henna tattoos, it is considered probable that they are mostly caused by p-phenylenediamine that has been added for colour intensification ("black henna").

Lawason is stereoisomeric to juglone, an ingredient of the walnut shell that can be found in self-tanning products.

Literature
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  1. Almeida PJ et al (2012) Quantification of p-phenylenediamine and 2-hydroxy-1,4-naphthoquinone in henna tattoos. Contact dermatitis 66:33-37.

  2. Boschnakow A et al. (2003) Temporary tattooing with henna induces contact allergy to textile dyes. JDDG 1: 962-964

  3. Jovanovic DL et al.(2009) Allergic contact dermatitis fromtemporary henna tattoo. J Dermatol 36:63-65.
  4. Polat M et al. (2009) Allergic contact dermatitis to pure henna. Dermatol Online J 15:15.