Guajaci lignum

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 29.10.2020

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Synonym(s)

Frenchwood; Guaiac wood

Definition
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Guajaci lignum, also known as Frenchwood or guaiac wood, is a drug used in herbal remedies for the supportive treatment of rheumatic complaints.

Ingredients
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Guajaci lignum contains 25% guaiac resin in the dark heartwood and about 3% resin in the yellowish-white sapwood, which consists of alpha- and beta-guaiaconic acid, guajaret acid and guaiaconic acid. Other ingredients are essential oil, phytosterol resin, triterpene type saponins and 12 to 15 % lignans.

Effects
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Guajaci lignum has antiphlogistic, spasmolytic and diuretic effects. The antiphlogistic effect is achieved by inhibiting the cyclooxygenase by lignans and guajazules. Guaiartes acid suppresses the NO formation by neutrophil granulocytes that occurs during the inflammatory reaction.

Field of application/use
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Guaiac wood is used as a supporting treatment for rheumatic complaints.

Dosage
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The average daily dose is 4.5 g of the drug.

Undesirable effects
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There are no known adverse effects.

Contraindication
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There are no known contraindications.

Literature
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  1. Schilcher H (2016) Leitfaden Phytotherapie, Urban & Fischer Verlag, Munich, p. 147 f.

Outgoing links (2)

Lignane; Saponins;