DefinitionThis section has been translated automatically.
Grindelia herba, the Grindelia herb consists of the dried flowering stem tips and leaves of the gumweedcollected during the flowering season.
HMPC monograph: Traditional-use:cough due to colds
ESCOP monograph: productive cough, catarrh of the upper respiratory tract
Commission E-monograph: Catarrh of the upper respiratory tract.
IngredientsThis section has been translated automatically.
Diterpenes (esp. Grindelic acid), flavonoids (camphorol ether, luteolin, quercetin and quercetin ether), polyynes (matricarianol and matricaria ester), essential oil (about 0.3%), triterpene saponins (with bayogenin, echinocystic acid, oleanolic acid, grindeliasapogenin D and polygalic acid as aglycones), tannins, phenolic carboxylic acids (chlorogenic acid, p-coumaric acid, ferulic acid, caffeic acid and vanillic acid, hentriacontane) and phytosterols.
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ContraindicationThis section has been translated automatically.
Contraindicated in case of allergy to one of the ingredients, children and adolescents under 18 years, no data for pregnancy and lactation.
Note(s)This section has been translated automatically.
Grindelia herba is used in folk medicine for catarrh of the upper respiratory tract. Furthermore, Grindelia herba is also used for cystitis, nephritis, arteriosclerosis, gastrointestinal cramps and other diseases. The extracts have been shown to have an antifungal effect (Zabka M et al. 2011).
Grindelia herba extracts have been successfully used in toxic dermatitis (Canavan D et al 2005).
Extracts of Grindelia herba are used in cosmetic formulations.
LiteratureThis section has been translated automatically.
- Canavan D et al. (2005) Successful treatment of poison oak dermatitis treated with Grindelia spp. (Gumweed). J Altern Complement Med 11:709-710.
- Pinkas M et al (1978) Phenolic components from some species of Grindelia (author's transl) Ann Pharm Fr 36(3-4):97-104.
- Zabka M et al. (2011) Promising antifungal effect of some Euro-Asiatic plants against dangerous pathogenic and toxinogenic fungi. J Sci Food Agric 91:492-497.
- https://medicinalplantsencyclopedia.info/grindelia.php.
- https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-grindelia-robusta-nutt-grindelia-squarrosa-pursh-dunal-grindelia_en.pdf
