Garlic

Spice and medicinal plant from the allium family (Alliaceae). The garlic bulb is a roundish to egg-shaped white bulb with a diameter of around 3.0 cm and a pungent odor. Several secondary bulbs are usually attached to the main bulb. Allium sativum is the parent plant of Allii sativi bulbus , a drug that has been positively monographed by Commission E and the WHO.

HMPC monograph: Traditional-use: traditional herbal medicinal product for the prevention of arteriosclerosis, also for the relief of symptoms of the common cold.

The quality of garlic powder is defined in the European Pharmacopoeia (Ph. Eur.).

ESCOP - Monograph: preventive against atherosclerosis, for elevated blood lipid levels which cannot be adequately controlled by dietary measures, supportive for high blood pressure; also for infections and catarrh of the upper respiratory tract.

Commission E-Monography: support for dietary measures in the case of elevated blood lipid levels and for the prevention of age-related vascular changes

Empirical medicine: adjuvant for lowering blood pressure, digestive complaints, improving vigilance, anthelmintic for pinworms

Ingredients of the fresh garlic bulb: sulphur-containing gamma-glutamyl peptides, odorless, water-soluble (S-allylcysteine sulphoxide). Furthermore, several enzymes such as oxidases, catalases, dehydrogenases, lyases and various vitamins. vitamins. After subsequent crushing, the alliin produces the degradation products allicin (unstable) and ajoene.

The different processing methods result in different compositions of the preparations.

Garlic oil (Oleum Allii sativi), an essential oil, is obtained by steam distillation of the garlic bulb. Garlic oil contains mainly diallyl disulphide (60%), which is responsible for the characteristic odor, as well as tri- and polysulphides; furthermore alliiin and ajoene in variable composition.

One of the oldest medicinal and spice plants on earth. In India, China, Africa and the Balkan countries, its healing power has been well known for centuries, which explains its high consumption. Even folk medicine in our latitudes has been using garlic since ancient times for its antibacterial, fungicidal (the biologically active ingredient of garlic "Ajoen" has proven fungicidal properties), antiseptic, spasmolytic, carminative, anthelmintic and other effects in a wide variety of remedies for treating gastrointestinal complaints, various skin diseases, inflammations, rheumatism, ulcers, cramps, pain, etc.

Average daily dose 4 g fresh garlic cloves

EMA: for the prevention of arteriosclerosis. Single dose: in powder form: 300 mg to 750 mg , daily dose: 900-1380 mg divided into 3-5 single doses, in liquid form: single dose: 110-220 mg 4 times / day, daily dose: 440-880 mg .

for colds: single dose: 100-200 mg 1-2 times / day, daily dose: 100-400 mg

Gastrointestinal complaints or allergic reactions. Change in bleeding time, no combination with warfarin sodium.

Patients on saquinavir/ritonavir therapy: risk of decrease in plasma concentration with loss of virological response and possible resistance to one or more components of the antiretroviral preparation.

As drug: children and adolescents under 18 years of age.

In the absence of sufficient data, use during pregnancy and lactation is not recommended.

Oral anticoagulation therapy and/or an antiplatelet agent: bleeding times may be prolonged

Patients on saquinavir/ritonavir therapy: risk of decrease in plasma concentration with loss of virological response and possible resistance to one or more components of the antiretroviral drug.

• Beni-cur N® coated film-coated tablet
• Kwai forte® 300 mg coated tablets (300mg garlic bulb powder). Dosage depending on tolerance up to 3x1 Drg./day
• Kwai N Dragees® (100mg garlic bulb powder). Dosage depending on tolerance up to 3x3 dragees/day
• Sapec® coated tablets (300mg garlic powder). Dosage: 3x1 daily 1 Drg.

Garlic consumption should be avoided for 7 days prior to surgery due to the postoperative bleeding risk.

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