Garden rue

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 07.06.2024

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Synonym(s)

Cross rue; Diamond; Garden rue (engl.); rue des jardins (frz.); Ruta graveolens L.; Wine rue

Occurrence
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Origin and distribution: mainly in the Mediterranean area. Garden plant, sometimes overgrown.

Field of application/use
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Uses: Various species of the genus Ruta (family Rutaceae) have been used medicinally for centuries. Garden rue is used as a vein remedy, diuretic and gastrointestinal remedy.

Studies in animals show a relaxing effect on the tracheal rings, i.e. a relaxing effect on the bronchi with indications of benefits for bronchial diseases.

The herb of the plant was used phytotherapeutically, see Ruta graveolentis Herba

Undesirable effects
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Allergological information: Contains various coumarin derivatives, e.g. rutarin and phototoxic psoralens (xanthotoxin and bergapten); furthermore the isoquinoline alkaloid dictamine which also has a photosensitizing effect. Sensitizing potency: Apparently weak. Frequency of photosensitization: Rare.

Clinical picture
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As a side effect: Phototoxic dermatitis.

Note(s)
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Ruta graveolens is the parent plant of Ruta graveolentis Herba, the officinal (DAC86), medicinally used garden rue herb. Rutae graveolentis Herba is the starting product of Oleum Rutae.

Literature
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  1. Schempp CM et al. (1999) Dermatitis bullosa striata pratensis caused by Ruta gravolens L. (garden rue) Hautarzt 50: 432-434
  2. Águila L et al. (2015) Relaxant effects of a hydroalcoholic extract of Ruta graveolens on isolated rat tracheal rings. Biol Res: 48(1):28. doi: 10.1186/s40659-015-0017-8. PMID: 26044818; PMCID: PMC4462083.