Synonym(s)
DefinitionThis section has been translated automatically.
Medicinally used, Ph.Eur.2 monogrpahized, dried bark of the twigs and the younger stems of the buckthorn, both of Franula alnus the fine-leaved buckthorn and the American buckthorn, s.a. Rhamni purshianae cortex.
Quality is laid down in the European Pharmacopoeia (Ph. Eur.).
HMPC monograph: well-established use: Internal: short-term treatment of constipation, 1 week
ESCOP monograph: short-term treatment of constipation.
Commission e-monograph: constipation
Empirical medicine: abscesses, arteriosclerosis, blood purification, obesity, bile flow congestion, biliary insufficiency, gallstones, grind,
hemorrhoids, scabies, swelling of the liver, inflammation of the oral mucosa, constipation, bloating, dropsy, gingivitis
IngredientsThis section has been translated automatically.
Efficacy determining ingredients: numerous hydroxyanthracene glycosides, especially of the aloe emodin type, as well as glycosides of emodin (of which 80-90% are C-glycosides of the aloe type, so-called cascarosides); furthermore frangulin A and frangulin B and saponins, more rarely also bitter substances andtannins.
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EffectsThis section has been translated automatically.
Laxative, anti-absorptive.
Field of application/useThis section has been translated automatically.
Indication: chronic constipation,
DosageThis section has been translated automatically.
0.5-2.0g as 10% decoction 20.0g. Duration of the intake 1-2 weeks.
The fresh drug has emetic effect (fresh bark contains anthrones and dianthrones which are no longer present in deposited bark).
ContraindicationThis section has been translated automatically.
Contraindications: Ileus, acute inflammatory bowel disease, unclear abdominal pain
Note(s)This section has been translated automatically.
Not for children <12 years
LiteratureThis section has been translated automatically.
- Brkanac SR et al. (2015) Toxicity and antioxidant capacity of Frangula alnus Mill. bark and its activeemodin. Regul Toxicol Pharmacol 73:923-929.
- Demuth G et al.,(1978) Investigations on anthraquinone glycosides of Rhamnus species, V Emodin-8-O-beta-gentiobioside,e a new O-glycoside from Rhamnus frangula. Planta Med 33:53-56.
- Koyama J et al.(2001) Inhibitory effects of anthraquinones and bianthraquinones on Epstein-Barr virus activation. Cancer Lett 170:15-18.
- Sadowska B et al. (2014) Vaccinium myrtillus leaves and Frangula alnus bark derived extracts as potential antistaphylococcal agents. Acta Biochim Pol 61:163-169.
- https://arzneipflanzenlexikon.info/faulbaum.php
- https://heilkraeuter.de/lexikon/faulbaum.htm
- https://www.awl.ch/heilpflanzen/rhamnus_frangula/faulbaum.htm
Prof. Dr. med. Peter Altmeyer
Prof. Dr. med. Martina Bacharach-Buhles