Echinacea purpurea herba

Echinaceae purpureae herba, is an officinal preparation (Ph.Eur.8; Monograph: Commission E,WHO, ESCOP) from the whole or cut aerial parts of the plant, see under Echinacea
Quality is defined in the European Pharmacopoeia (Ph. Eur.).:

HMPC monograph: well-established use: Internal: Prevention and therapy of colds. External: Traditional-use: Superficial wounds.

ESCOP mon ograph: Internal: recurrent upper respiratory (common cold) and urinary tract infections; External: superficial wounds.
Commission E monograph: recurrent respiratory and urinary tract infections.

Empirical medicine: herpes simplex (external), adjuvant in tumor diseases.

Caffeic acid derivatives (caftaric acid, chicory acid), flavonoids, essential oil, polysaccharides, etc.

Promotion of wound healing, increase in phagocytosis of granulocytes, activation of fibroblasts, antiphlogistic, non-specific immune modulation.

Internal: supportive therapy for recurrence infections of the urinary and respiratory tract. Also for prophylaxis of infections.
External: Supportive therapy for chronic wounds with poor healing

With parenteral application, dose-dependent fever reactions, also nausea and vomiting. Allergic reactions possible with parenteral application. Caution with atopics!
In case of application > 8 weeks possibly liver-toxic!

Allergy to one of the ingredients. For fundamental considerations, not to be used in progressive systemic diseases. HIV infection, multiple sclerosis, autoimmune diseases.
No sufficient data for safety in pregnancy and lactation, the sparse data to date (several hundreds of exposed pregnancies): no adverse effects on pregnancy or fetal/neonatal health.

Do not apply externally to the breast in nursing mothers!

Children under 12 years due to lack of data. Pregnancy and lactation due to lack of data

Cefatox effervescent tablets, 1-0-1/dayEchinacin
Liquidum Madaus, initial 2.5ml, then 1.25ml every 1-2 hoursEchinacin
Juice Madaus, 5-5-5 ml/dayEsberitox
mono tablets/drops (dosage according to instructions)

Furthermore, combination preparations of Echinacea pallida root + Echinacea purpura root + wild indigo root (Esberitox N solution/tablets)

Do not combine with immunosuppressants!

1. Ardjomand-Woelkart K et al. (2016) Review and Assessment of Medicinal Safety Data of Orally Used Echinacea Preparations. Planta Med 82(1-2):17-31.
2. Manayi A et al. (2015) Echinacea purpurea: Pharmacology, phytochemistry and analysis methods. Pharmacogn Rev 9:63-72.
3. Goey AK et al (2013) The effect of Echinacea purpurea on the pharmacokinetics of docetaxel. Br J Clin Pharmacol 76:467-474.
4. Moltó J et al (2012) Herb-drug interaction between Echinacea purpurea and etravirine in HIV-infected patients. Antimicrob Agents Chemother 56:5328-5331.
5. Izzo AA (2012) Interactions between herbs and conventional drugs: overview of the clinical data. Med Princ Pract 21:404-428.
6. Yamada K et al (2011) A comparison of the immunostimulatory effects of the medicinal herbs Echinacea, Ashwagandha and Brahmi. J Ethnopharmacol 137:231-235.
7. hhttps://arzneipflanzenlexikon.info/echinacea.php.
8. https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-echinacea-purpurea-l-moench-herba-recens_en.pdf
9. Wenigmann M. (2017) Phytotherapy medicinal drugs, phytopharmaceuticals, application. Urban & Fischer, pp. 176-177
10. Miller LG (1998) Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions. Arch Intern Med. 9;158(20):2200-2211. doi: 10.1001/archinte.158.20.2200. PMID: 9818800.