Cumestane

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 16.04.2024

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Synonym(s)

Coumaronocoumarins

Definition
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Cumestans, also known as coumaronocoumarins, are secondary plant substances belonging to the polyphenols, which are mainly found in legumes.

General information
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Cumestans, also known as coumaronocoumarins, are secondary plant substances belonging to the polyphenols, which are mainly found in legumes.

Examples from the coumestan family are: Lucernol (2,3,9-trihydroxycumestane, Medicago sativa), sativol (4,9-dihydroxy-3-methoxycumestane, Medicago sativa), psoralidin (3-hydroxy-9-methoxy-2-χ,χ-dimethylallylcumestane, Psoralea corylifolia), 2-hydroxy-1,3-dimethoxy-8,9-methylenedioxycumestane (Swartzia leiocalycina). Some coumestan representatives are classified as phytoestrogens (coumesterol, 4'-methoxycumestrol), compounds that are similar in structure and effect to female sex hormones.

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Phytoestrogens;