Convallariae majalis herba

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 22.11.2024

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Definition
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Dried herb of the lily of the valley. The herb is poisonous, it contains cardiac steroids: cardenolides (cardenolide glycosides), especially convallatoxin, convalloside and convallotoxol.

HMPC: not processed

ESCOP: not edited
Commission E monograph (old: 1990): mild heart failure (NYHA stage II on exertion), old-age heart and chronic cor pulmonale, now obsolete, see below

Historically, folk medicine: cardiac insufficiency Now obsolete due to the limited therapeutic range (strong toxic effect of cardenolides!).

Effects
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Positively inotropic, lowers increased left ventricular end-diastolic pressure, economizes cardiac work, lowers pathologically increased venous pressure, tonifies veins, diuretic effect, natriuretic and kaliuretic.

Undesirable effects
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Nausea, vomiting, diarrhea, cardiac arrhythmia

Contraindication
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Therapy with digitalis glycosides, potassium deficiency states

Interactions
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Enhancement of the effect of quinidine, calcium, saluretics, laxatives, glucocorticoids.

Literature
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  1. https://arzneipflanzenlexikon.info/maigloeckchen.php
  2. Wenigmann M. (2017) Phytotherapy medicinal drugs, phytopharmaceuticals, application. Urban & Fischer, pp. 153-154