Chelidonii herba

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 16.04.2025

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Official preparation of celandineextracts

Definition
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Dried celandine consisting of leaves, flowers and stems.

Quality recognized in the European Pharmacopoeia (Ph.Eur. 8.0).

HMPC: Originally the classification traditional-use was planned. However, due to the risk-benefit ratio, it was not recommended because of the side effects on the liver.
ESCOP monograph: Symptomatic treatment of mild cramps in the upper gastrointestinal tract, mild biliary complaints, dyspeptic complaints, flatulence, bloating.
Commission E-monograph: Cramp-like complaints in the biliary tract and gastrointestinal tract.

Empirical medicine: Gallstone, antispasmodic preparation, against jaundice, toothache. The milky juice: Warts (external) due to the cytotoxic, antimicrobial effect

Spectrum of action
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Slightly spasmolytic in the upper digestive tract, choleretic, cholekinetic, antiphlogistic, analgesic, central depressant, antimicrobial, cyotoxic.

Undesirable effects
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Increase in liver enzyme activities and serum bilirubin

Contraindication
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Allergy to any of the ingredients. History or manifest liver disease, concomitant administration of other preparations toxic to the liver, pregnancy and lactation, children << 12 years.

Preparations
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largely withdrawn from the market - still contained in Iberogast® alongside 7 other plant extracts.

Note(s)
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Ingredients: alkaloids, especially benzylisoquinoline type (e.g. coptisine, chelidonine, sanguinarine), chelidonic acid and caffeic acid derivatives.

Literature
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  1. https://arzneipflanzenlexikon.info/schoellkraut.php
  2. Wenigmann M.(2017) Phytotherapie Arzneidrogen Phytopharmaka Anwendung. Urban und Fischer: 5.104 Celandine (Chelidonii herbae): S 190-192
  3. Blaschek W (2015) Wichtl tea drugs and phytopharmaceuticals. A handbook for practice. Wissenschaftliche Verlagsgesellschaft Munich. S 169-172